Griffith Jones may refer to:

• Griffith Jones (Llanddowror) (1684–1761), Llanddowror, who established circulating schools in Wales
  • Ysgol Griffith Jones, Carmarthenshire, UK, a school named after the educator
• Griffith Jones (mayor), appointed to the Supreme Court of Pennsylvania in 1690, later Mayor of Philadelphia
• Griffith Jones (actor) (1909–2007), actor, who played Caryl Sanger in the film Escape Me Never (1935)
• Griffith Jones (priest) (1684–1761), Welsh Anglican priest who promoted Methodism
• Griffith Arthur Jones (1827–1906), Welsh Anglican priest
• Griffith Hartwell Jones (died 1944), Professor of Latin at the University of Wales, Cardiff
• Griff Rhys Jones, British comedian, writer, and actor
• Griffith Rhys Jones (1834-1897), Welsh conductor
• Mervyn Griffith-Jones (1909-1979), British lawyer and judge