Sergio Di Zio (born September 20, 1972) is a Canadian actor. He starred in the television series Flashpoint as Michelangelo "Spike" Scarlatti until the show concluded on December 13, 2012.

Di Zio's other works include The Lookout, Cinderella Man, Senior Trip; the television series This is Wonderland, Northern Town; as a voice actor for the animated series Stoked and Babar and the Adventures of Badou. He also appeared in the stage debut of Léo written by Rosa Labordé for which he received a Dora Award nomination in 2006. Di Zio was recently part of an animated show called Grojband, until the show concluded in May 2015.